General description
The platelet and endothelial cell adhesion molecule 1 (PECAM1) is also termed as cluster of differentiation 31 (CD31). It belongs to the immunoglobulin (Ig) superfamily. This gene codes for a 130kDa protein and is located on human chromosome 17. PECAM1 is expressed on the surface of circulating platelets, monocytes, neutrophils and selected T-cell subsets.
Immunogen
The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713.
Immunogen Range: 686-735
Biochem/physiol Actions
The platelet and endothelial cell adhesion molecule 1 (PECAM1) participates in leukocyte-endothelial interaction.This protein has a major role in the adhesion cascade leading to leukocyte extravasation during the inflammatory process. PECAM1 also plays a role during the development of T cell.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 82 kDa |
| species reactivity | rat, human, mouse |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:20000,immunofluorescence: 1:100-1:500,western blot: 1:500-1:1000 |
| NCBI accession no. | P16284 |
| UniProt accession no. | P16284 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr713) |
| Gene Information | human ... PECAM1(5175) |
