Immunogen
Recombinant protein encompassing a sequence within the center region of human Cofilin 1.
Application
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Biochem/physiol Actions
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM]
Features and Benefits
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Physical form
Phosphate-buffered saline, no preservative added.
Other Notes
Purification: Affinity purified by Protein G
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | GT567, monoclonal |
| form | buffered aqueous solution |
| mol wt | 19kDa |
| species reactivity | rat, mouse, human |
| concentration | 1mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable,indirect immunofluorescence: suitable,western blot: suitable |
| isotype | IgG2a |
| UniProt accession no. | P23528 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CFL1(1072) |
