产品介绍
Product Description
Application
ARP 101 is a MMP-2 selective inhibitor. ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development, and embryogenesis.
Biochem/physiol Actions
ARP 101 is a MMP-2 selective inhibitor (Gelatinase A, EC 3.4.24.24; TBE-1; LG4A; MONA; Type IV Collagenase). ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development and embryogenesis. IC50 = 0.81 nM on MMP-2.
ARP 101 is a MMP-2 selective inhibitor.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| solubility | DMSO: >20 mg/mL,H2O: insoluble |
| web metadata keyword.default | ARP 101 (2R)-2-[([1,1′-Biphenyl]-4-ylsulfonyl)amino] compound,ARP 101 (R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide,ARP 101 Gelatinase A inhibitor,ARP 101 IC50 0.81 nM,ARP 101 MMP-2 inhibitor,ARP 101 MMP-2 selective inhibitor,ARP 101 Type IV Collagenase inhibitor,ARP 101 angiogenesis inhibitor,ARP 101 cancer metastasis research,ARP 101 for tissue remodeling,ARP 101 research grade,ARP 101 wound healing agent,MMP-2 inhibitor ARP 101 procurement,Sigma-Aldrich ARP 101,Sigma-Aldrich MMP-2 inhibitor ARP 101 |
| storage temp. | −20°C |
| SMILES string | CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c2ccccc2 |
| InChI | 1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1 |
| InChI key | DGZZVIWCMGVHGV-LJQANCHMSA-N |
