General description
Glutathione peroxidase 3 (GPX3) belongs to the glutathione peroxidase (GPX) family. It is located on human chromosome 5q23.
Immunogen
Peptide with sequence C-NQFGKQEPGENSE from the internal region of the protein sequence according to NP_002075.2.
Application
Anti-GPX3 antibody has been used in western blotting.
Biochem/physiol Actions
Glutathione peroxidase 3 (GPX3) blocks oxidative damages by decreasing redundant reactive oxygen species (ROS). It plays a major role in solid tumors and hematological malignancies. GPX3 also plays an important role in the effectiveness of leukemic stem cells (LSCs) and self renewal actions of hematopoietic stem cells (HSCs).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | mouse, canine, rat, human |
| technique(s) | immunohistochemistry: suitable,indirect ELISA: suitable,western blot: suitable |
| UniProt accession no. | P22352 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GPX3(2878) |
