产品介绍
Product Description
Biochem/physiol Actions
Allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake.
SRI-32743 is an allosteric modulator of monoamine transporters that acts as partial antagonists of dopamine uptake. SRI-32743 attenuates Tat (the HIV regulatory protein transactivator of transcription) induced inhibition of DAT-mediated dopamine uptake. Also, it alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear (Warmed) |
| storage temp. | 2-8°C |
