产品介绍
Product Description
Application
Romifidine hydrochloride may be used to study its effects on sedation and pain management in animal models.
Biochem/physiol Actions
Romifidine is an α2-adrenergic receptor (α2-adrenoceptor) agonist with in vivo sedative and analgesic efficacy. Romifidine depresses excitatory postsynaptic potential in a neonatal rat hemisected spinal cord preparation ex vivo (high/low intensity e.p.s.p. EC50 = 23.4/22.0 µM), reversible by the selective α2-adrenoceptor antagonist atipamezole.
Disclaimer
Hygroscopic
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | FC1=CC=CC(Br)=C1NC2=NCCN2.Cl |
