General description
Extracellular matrix protein 1 (ECM1) is a glycoprotein. It is expressed in skin and other tissues. The gene encoding this protein is localized on human chromosome 1q21.2.
This ELISA antibody pair detects Human Extracellular Matrix Protein 1 (ECM1)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Extracellular matrix protein 1 (ECM1) has a role in cell proliferation, mineralization and angiogenesis. The protein has been shown to have a role in cancer invasion and progression. It is associated with hepatocellular carcinoma. Mutations in the ECM1 gene have been linked to lipoid proteinosis. The protein also promotes the Warburg effect, which is an oncogenic switch that allows cancerous cells to take in more glucose than non-cancerous cells.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type plasma sample type cell culture supernatant(s) sample type serum sample(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 24 pg/ml |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... ECM1(1893) |
