产品介绍
Product Description
General description
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Immunogen
A phospho specific peptide corresponding to residues surrounding S386 of human IRF3
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
技术参数
Specifications
| biological source | rabbit |
| Quality Level | 100 |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | human, rat |
| concentration | 1 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | Q14653 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer386) |
| Gene Information | human ... IRF3(3661) |
