Immunogen
The epitope recognized by PLA0300 maps to a region between residue 1531 and 1581 of human Cofactor Required for Sp1 Transcriptional Activation 1/Thyroid Hormone Receptor-Associated Protein Complex Component using the numbering given in entry NP_004765.2 (GeneID 5469).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
CSP1/TRAP220 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15648].
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human, mouse |
| concentration | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:500-1:2,000,immunoprecipitation (IP): 2- 10 μg/mg,western blot: 1:500- 1:2,500 |
| accession no. | NP_004765.2 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | goat ... CRSP1/TRAP220(5469) |
