General description
The Mouse ICAM-1 (Intercellular Adhesion Molecule-1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of mouse ICAM-1 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Mouse ICAM1
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Intercellular adhesion molecule-1 (ICAM-1) is a member of immunoglobulin (Ig) superfamily. It is an inducible transmembrane glycoprotein. ICAM-1 mediates adhesion of circulating leukocytes to the endothelial membrane and blood vessel. ICAM-1 might cause atherosclerosis and the polymorphism in ICAM-1 has reduced risk to cardiovascular diseases. IL-6 induces the upregulation of ICAM-1 and leads to metastasis of osteosarcoma cells. ICAM-1 causes invasion and metastasis of breast cancer cells. ICAM-1 is an important receptor for rhinovirus and Haemophilus influenzae binding. Upregulation of ICAM-1 in the respiratory tract of chronic airway limitation patients increases the risk of respiratory infections.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | mouse |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable,capture ELISA: suitable |
| input | sample type serum sample type plasma sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 20 pg/mL standard curve range: 24.69-6000 pg/mL |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | mouse ... Icam1(15894) |
