General description
Anti-CXCR7 Antibody detects endogenous levels of total CXCR7 protein.
CXC- Chemokine receptor 7 (CXCR7) protein is a seven-transmembrane G-protein coupled receptor (GPCR). It is expressed in the heart tissues, fetal hematopoietic cells, embryonic neuronal, and activated endothelium. CXCR7 gene is mapped on the human chromosome at 2q37.3.
Immunogen
The antiserum was produced against synthesized peptide derived from human CXCR7.
Immunogen Range: 311-360
Biochem/physiol Actions
CXC- Chemokine receptor 7 (CXCR7) protein interacts with chemokine ligands CXCL11 and CXCL12. This protein shuffles between the plasma membrane and endosomal compartments irrespective of the presence of a ligand such as CXCL11 and 12. CXCR7 protein plays a role in cell survival and cell adhesion to the endothelium. This protein tends to regulate the activity of CXCR4.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 41 kDa |
| species reactivity | rat, mouse, human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:1000,immunofluorescence: 1:100-1:500,western blot: 1:500-1:1000 |
| NCBI accession no. | P25106 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CXCR7(57007) |
