General description
Factor V is a single chain glycoprotein involved in the blood coagulation cascade. It is the procofactor of Va which accelerates the conversion of prothrombin to thrombin.
Application
Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of Coagulopathic bleeding which occurs following injury and is a leading cause of in hospital deaths.
Physical form
Aqueous solution containing 50% (v/v) glycerol
Other Notes
One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.
View this factors role in the Coagulation Cascade.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
| biological source | human |
| Quality Level | 200 |
| form | aqueous glycerol solution |
| specific activity | ≥25 units/mg protein |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | P12259 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... F5(2153) |
