General description
The antibody HL-37 reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Immunogen
Burkitt′s lymphoma cell line Raji
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Features and Benefits
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Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | HL-37, monoclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | flow cytometry: suitable |
| isotype | IgG3 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... HLA-DQA1(3117) |
