General description
Matrix Metalloproteinase-9 encodes an enzyme that degrades type IV and V collagens.
Matrix metalloproteinase-9 (MMP-9) is a pro-inflammatory, zinc-dependent proteinase which is also known as 92kDa gelatinase. It is produced by various cells like granulocytes and mononuclear cells. The gene encoding it is localized on human chromosome 20q11.2-q13.1.
Immunogen
purified, NSO-derived, recombinant mouse matrix metalloproteinase-9.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)
Biochem/physiol Actions
Matrix metalloproteinase-9 (MMP-9) has been studied as a biomarker of nervous tissue inflammation in multiple sclerosis (MS).
This antibody recognizes pro and active mouse MMP-9. Immunoblotting and ELISA applications show an ~10% cross-reactivity with recombinant human MMP-9.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | mouse |
| technique(s) | immunohistochemistry: 5-15 μg/mL using cells or tissues,immunoprecipitation (IP): 25 μg/mL using conditioned media of transfected NSO cells,western blot: 0.25 μg/mL |
| UniProt accession no. | P41245 |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Mmp9(17395) |
