General description
EGFR is a transmembrane tyrosine kinase of HER/erbB protein family. EGFR somatic mutations such as L858R in exon 21 and short in-frame deletion of E746-A750 in exon 19 are present in a subset of lung adenocarcinoma.
Immunogen
Synthetic EGFR peptide with L858R mutation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| recombinant | expressed in proprietary host |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | SP125, monoclonal |
| species reactivity | human (tested) |
| technique(s) | immunoblotting: 1:200,immunohistochemistry: 1:100 |
| isotype | IgG |
| UniProt accession no. | P00533 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... EGFR(1956) |
