General description
CK1γ1 or casein kinase 1, gamma 1 is belonging to the most abundant serine/threonine kinase in eukaryotic cell extracts which is mainly involved in growth and morphogenesis of eukaryotic cells. Casein kinase 1, gamma 1 possesses a C-terminal most terminal sequence motif (MTM), which it shares with CSNK1G2 and CSNK1G3 which is associated with heterologous carboxy-terminal sequences. Casein kinase 1-gamma couples Wnt receptor activation to the cytoplasmic signal transduction apparatus.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| product line | PRECISIO® |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 66-98 nmol/min·mg |
| mol wt | ~82 kDa |
| NCBI accession no. | NM_022048 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... CSNK1G1(53944) |
