Immunogen
The epitope recognized by PLA0163 maps to a region between residue 2442 and the C-terminus (residue 2492) of human alpha thalassemia/mental retardation syndrome X-linked using the numbering given in entry NP_000480.2 (GeneID 546).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
ATRX (alpha-thalassemia mental retardation X-linked) is a chromatin remodeling protein and transacting regulator of globin gene expression that has been linked to several X-linked mental retardation syndromes and hematologic diseases such as myelodysplasia. ATRX possesses an ATPase/helicase domain and is related to the SWI/SNF family of proteins. Mutations in ATRX have been demonstrated to cause changes in DNA methylation patterns and gene expression important to development.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:500-1:2,000,immunoprecipitation (IP): 2-10 μg/mg,western blot: 1:1,000-1:5,000 |
| accession no. | NP_000480.2 |
| UniProt accession no. | P46100 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| Gene Information | rabbit ... ATRX(546) |
