General description
The PTGER3 (prostaglandin E receptor 3) gene is mapped to human chromosome 1p31.1 and encodes a Gαi coupled receptor protein. It is predominantly localized to the brain in the neurons and activated glial cells. Anti-PTGER3 antibody detects endogenous levels of total PTGER3 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human PTGER3.
Immunogen Range: 16-65
Biochem/physiol Actions
Prostaglandin E receptor 3 (PTGER3) serves as a receptor for prostaglandin (PG) E1 and E2, to carry out a number of physiological processes. PTGER3 specifically functions to reduce adenylyl cyclase action. It is involved in the activation of the Ras signaling pathway.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 43 kDa |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:10000,immunofluorescence: 1:100-1:500 |
| NCBI accession no. | P43115 |
| UniProt accession no. | P43115 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... PTGER3(5733) |
