产品介绍
Product Description
|
规格 |
|
| Accession Number: | NP_002729.2 |
| Shipping Condition: | Dry Ice |
| Expression System: | Insect |
| Protein Form: | Full Length, Active |
| Research Category: | Drug Development |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Gene ID (Entrez): | PRKCB |
| Molecular Weight: | 103.7 kDa |
| Gene Alias: | PKC-beta; PKCB; PRKCB; PRKCB2 |
| KinaseFamily: | PKC Kinase Family |
| Protein Tag: | GST Tag |
|
储存 |
|
|
Storage Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
|
描述 |
The PKC family of serine/threonine kinases, including PRKCB2 (PKC beta II), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
